Find clinical trials and studies actively recruiting non-smokers for various health research initiatives. Explore non-smoker research studies on DecenTrialz.

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Found 214 Actively Recruiting clinical trials

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Actively Recruiting

Healthy Volunteer

The purpose of the study is to evaluate the safety of SPH9788 tablets in healthy subjects.

Age: 18Years - 45YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

The objective of this clinical study is to evaluate the safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of SV003 in healthy subjects.

Age: 18Years - 45YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-201 in healthy participants.

Age: 19Years - 55YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

The main purpose of this study is to evaluate the safety, tolerability and pharmacokinetics (PK) of Debio 1453P compared to placebo across different dose levels in healthy adults after single and repeated oral dosing.

Age: 18Years - 55YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

YH35995 is being developed as a treatment for the neurological symptoms of Gaucher Disease type 3. This study is a first-in-human (FIH), phase 1, randomized, double-blind, placebo-controlled study of YH35995, which consists of two parts. In Part A (SAD), single ascending dose of YH35995 is administered to healthy male participants to assess its safety, tolerability, PK, and PD. In Part B (MAD), multiple ascending dose of YH35995 is administered to healthy male participants to assess its safety, tolerability, PK, and PD.

Age: 19Years - 45YearsMALEPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

The primary purpose of this study is to evaluate the effect of a high-fat, high-calorie meal on the relative bioavailability of NAL ER following single oral doses.

Age: 18Years - 60YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

The present study aims to use the SensMode System - a system composed of wearable devices for upper and lower limb movement analysis and electronic device for data acquisition and processing - on healthy subjects, subjects with idiopathic hyposmia, patients with Parkinson's disease, and subjects with de-novo drug-naïve extrapyramidal syndrome. The purpose is to identify normative data of objective motor measures obtained with such a system, as well as to increase knowledge about the potential contribution such a solution can make to the preclinical diagnosis of Parkinson's disease and the management of patients with this disease.

Age: 50Years - 80YearsAll GendersPhase Not Applicable
5 locations
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Actively Recruiting

Healthy Volunteer

Drug-Drug Interaction between DW4421 and three different kinds of NSAIDs

Age: 19Years - 50YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

This Phase 1 ethnobridging study will evaluate the pharmacokinetics, pharmacodynamics, and safety of AGA2118 in Japanese, Chinese, and Caucasian participants. Participants will be administered AGA2118 at the start of the study and followed for 85 days. Eighteen Japanese participants will be enrolled and randomized 1:1:1 to one of three doses of AGA2118 to be administered at a single timepoint. Following completion of dosing of the Japanese participants, 6 Caucasian participants will be enrolled to receive the highest dose at a single timepoint. They will be matched to Japanese participants (group average matching) by sex and weight. Additionally, 6 Chinese participants will be enrolled to receive a single administration of the highest dose. These participants may be enrolled at any time.

Age: 18Years - 65YearsAll GendersPhase 1
1 location
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Actively Recruiting

Healthy Volunteer

This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female

Age: 18Years - 55YearsFEMALEPhase 1
3 locations

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