Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04368702

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Led by Brigham and Women's Hospital · Updated on 2026-02-09

70

Participants Needed

2

Research Sites

424 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

CONDITIONS

Official Title

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have histologically or cytologically confirmed malignancy requiring radiation
  • Age 18 years of older
  • ECOG performance status 642 (Karnofsky 6560%, see Appendix A)
  • Ability to understand and the willingness to sign a written informed consent document.
  • Any further criteria listed in the specific disease site cohort
Not Eligible

You will not qualify if you...

  • History of allergic reactions attributed to gadolinium-based IV contrast (if contrast will be used)
  • Severe claustrophobia or anxiety
  • Participants who cannot undergo an MRI
  • Any other exclusion criteria listed in the specific disease site cohort

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Brigham & Women's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

2

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

R

Raymond Mak, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

5

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CONFIRM: Magnetic Resonance Guided Radiation Therapy | DecenTrialz