Actively Recruiting

Phase 3
Age: 50Years - 75Years
All Genders
NCT05675878

Confirmation of Diet as a Treatment for Gulf War Illness

Led by American University · Updated on 2024-07-09

160

Participants Needed

3

Research Sites

147 weeks

Total Duration

On this page

Sponsors

A

American University

Lead Sponsor

B

Boston University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention. The main objectives of this study are: 1) to confirm previous findings of treatment response to the diet in a larger and more diverse group; 2) to examine how changes in the nervous system may be the reason for improvement; and 3) to identify markers which change in the blood after one month on the diet. Participants will have baseline measures collected and then will be randomized into the intervention or wait-listed control group, which they will follow for one month before being reassessed.

CONDITIONS

Official Title

Confirmation of Diet as a Treatment for Gulf War Illness

Who Can Participate

Age: 50Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 50 to 75 years
  • Served in the 1990-1991 Persian Gulf War
  • Meet both CDC and Kansas definitions of Gulf War Illness
  • Stable medication regimen for at least 1 month and willing to keep medications and supplements stable during study participation
Not Eligible

You will not qualify if you...

  • Recent substance use disorder within the past year
  • Unwilling to stop using alcohol, tobacco (including vaping), or marijuana, or unwilling to change diet
  • Diagnosed seizure disorder or severe asthma requiring past hospitalization
  • Currently taking medications affecting glutamatergic or GABAergic neurotransmission without ability to wean off before participating

AI-Screening

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Trial Site Locations

Total: 3 locations

1

American University

Washington D.C., District of Columbia, United States, 20016

Actively Recruiting

2

Nova Southeastern University

Fort Lauderdale, Florida, United States, 33314

Actively Recruiting

3

Boston University

Boston, Massachusetts, United States, 02118

Actively Recruiting

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Research Team

H

Houra Taheri, PhD

CONTACT

K

Kathleen F Holton, PhD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Confirmation of Diet as a Treatment for Gulf War Illness | DecenTrialz