Actively Recruiting
Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
Led by Stanford University · Updated on 2025-06-26
200
Participants Needed
2
Research Sites
237 weeks
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
With an incidence rate of about 1%, Anorexia Nervosa (AN) is a serious mental disorder associated with high mortality, morbidity, and cost. AN in youth is more responsive to early treatment but becomes highly resistant once it has taken an enduring course. The first-line treatment for adolescents with AN is Family Based Treatment (FBT). While FBT can be delivered using videoconferencing (FBT-V), therapists' limited availability hampers scalability. Guided self-help (GSH) versions of efficacious treatments have been used to scale and increase access to care. The main aim of this proposed comparative effectiveness study is to confirm that clinical improvements in GSH-FBT are achieved with greater efficiency than FBT-V in generalizable clinical settings.
CONDITIONS
Official Title
Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants are 12-18 years of age
- Participants live with a family (some families may contain only one parent)
- Family members fluently speak and read English and have access to a computer with internet
- Participants meet DSM-5 criteria for AN (both subtypes)
- Expected body weight (EBW) above 75%
- Participants are medically stable for outpatient treatment according to recommended thresholds
- Participants are not engaged in another individual or family-based psychotherapy trial during the treatment sessions
- Medications for comorbid psychiatric disorders are allowed; randomization will balance groups
You will not qualify if you...
- Current psychotic illness, intellectual disability, or other mental illnesses preventing psychotherapy
- Current dependence on drugs or alcohol
- Physical conditions influencing eating or weight (e.g., diabetes mellitus, pregnancy)
- Previous Family Based Treatment (FBT)
- Inability of participant and/or family to speak and understand English
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Stanford University
Stanford, California, United States, 94305
Actively Recruiting
2
McMaster University
Hamilton, Ontario, Canada
Actively Recruiting
Research Team
A
Ainsley E Cogburn, B.S.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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