Actively Recruiting
A Randomized Controlled Trial Evaluating the Effect of qCON/qNOX-Guided Anesthesia on Clinical Outcomes in Pediatric Adenotonsillectomy
Led by Kayseri City Hospital · Updated on 2026-05-11
128
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the impact of Conox (qCON/qNOX)-guided anesthesia on drug use and recovery outcomes in children aged 3 to 12 years undergoing adenotonsillectomy. This study focuses on whether using the Conox device, which monitors brain activity related to sedation and pain, can improve anesthesia management and postoperative recovery compared to standard monitoring methods. Participants will be randomly assigned to one of two groups: one where anesthesia is guided by the Conox monitor providing qCON and qNOX values alongside standard monitoring, and another where anesthesia is managed using conventional clinical signs like heart rate and blood pressure. All children will receive a standardized anesthesia protocol including propofol, fentanyl, rocuronium, and sevoflurane. The trial will assess opioid use during surgery and other recovery factors. Throughout the study, researchers will monitor total intraoperative opioid consumption, emergence and extubation times, postoperative agitation, pain scores, and the relationship between Conox readings and vital signs. The trial aims to improve anesthetic drug use and recovery safety in pediatric adenotonsillectomy. Participation includes standard anesthesia care with additional monitoring and assessments during surgery and recovery.
CONDITIONS
Brief Title
Conox-Guided Anesthesia in Pediatric Adenotonsillectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 3 to 12 years
- ASA physical status I-II
- Scheduled for elective adenotonsillectomy
- No acute infection or systemic disease
- Parent or legal guardian able to provide written informed consent
You will not qualify if you...
- Skin lesions or anatomical abnormalities preventing placement of EEG electrodes
- History of neurological disease, including epilepsy or neurological syndromes
- Body mass index above the 95th percentile for age
- Previous pharyngeal surgery
- History of anesthesia-related complications
- Absence of written informed consent from a parent or legal guardian
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of surgery and anesthesia
Participants undergo anesthesia guided either by the Conox monitor with EEG-based indices or by standard clinical parameters during adenotonsillectomy surgery.
1 visit (in-person, surgery day)
Duration - Up to several hours post-surgery
Participants are monitored for recovery outcomes including emergence time, extubation time, postoperative agitation, and pain scores after surgery.
Approximately 1 follow-up visit (in-person)
Trial Site Locations
Total: 1 location
1
Kayseri Şehir Hastanesi
Kayseri, Turkey (Türkiye)
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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