Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT05271214

Conservative Management of Left Ventricular Assist Device Candidates

Led by Tel-Aviv Sourasky Medical Center · Updated on 2022-03-08

100

Participants Needed

1

Research Sites

521 weeks

Total Duration

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AI-Summary

What this Trial Is About

Left ventricular assist device (LVAD) candidates will be comprehensively evaluated at our center, including clinical evaluation, echocardiography, right heart catheterization, cardiopulmonary exercise test and laboratory exams. following this evaluation, patients will be treated with inotropes, diuretics, uptitrated neurohormonal therapy. vitamin and iron deficiencies will be corrected and the patients will be referred for coronary interventions and cardiac resynchronization therapy appropriately. The need for LVAD implantation will be reevaluated according to the patient's clinical condition, echocardiography and laboratory findings.

CONDITIONS

Official Title

Conservative Management of Left Ventricular Assist Device Candidates

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Left ventricular ejection fraction less than 35%
  • New York Heart Association Class III or IV symptoms
  • Brain natriuretic peptide levels above 450 pg/ml
  • Hospitalization for heart failure within the past 6 months
  • Maximal oxygen consumption less than 12 ml/kg/min
  • Intolerance to conventional heart failure therapy
Not Eligible

You will not qualify if you...

  • Pregnant or unable to give informed consent
  • Advanced liver disease (Child Pugh class B or C)
  • Advanced kidney disease (eGFR less than 30 ml/min)
  • Severe pulmonary disease
  • Severe peripheral vascular disease
  • Active malignancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel, 6423906

Actively Recruiting

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Research Team

O

Ofer Havakuk, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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