Actively Recruiting
Conservative Treatment With Blood Flow Restriction in Patients With Total ACL Rupture. "Randomized Clinical Trial"
Led by European University Cyprus · Updated on 2025-04-03
20
Participants Needed
2
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomised clinical trial is to evaluate the effects of exercise with blood flow restriction (BFR) in patients with a complete anterior cruciate ligament (ACL) rupture. The main questions it aims to answer are: 1. Does blood flow restriction adds any additional benefits to conservative treatment of the ACL? 2. Does bracing promotes spontaneous healing to the ACL Researchers will compare bracing and BFR to bracing and sham BFR to see if the intervention provides any additional benefits to the conservative management of this injury. Participants will: 1. Use a knee brace for 6 weeks with adjustments according to protocol 2. Follow and identical exercise plan with either BFR (intervention group) or BFR sham (control group) 3. Follow a home based exercise program.
CONDITIONS
Official Title
Conservative Treatment With Blood Flow Restriction in Patients With Total ACL Rupture. "Randomized Clinical Trial"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- MRI-confirmed complete rupture of ACL
- Ability to communicate and read fluently in Greek
- Willingness to keep the leg immobilised as required by the study protocol
You will not qualify if you...
- Heart disease
- Overweight
- Diabetes
- Pregnancy
- Thrombophilia
- Atrial fibrillation
- Heart failure
- Cancer
- Use of drugs that may increase blood clotting
- Use of hormones or contraceptives
- Any reason preventing the use of blood flow restriction (e.g., open wound, serious skin problems, allergies to cuff material)
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Trial Site Locations
Total: 2 locations
1
European University Cyprus
Nicosia, Cyprus, 2404
Actively Recruiting
2
European University Cyprus
Nicosia, Cyprus, 2404
Actively Recruiting
Research Team
A
Alexis N Pitsillides, PhD candidate
CONTACT
C
Christos Karagiannis, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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