Study Comparing Four Conservative Treatments for Shoulder Tendon Injury to Improve Sleep, Pain, and Function

What this Trial Is About

Rotator cuff injuries, particularly supraspinatus tendon tears, often cause severe pain that disrupts sleep quality. This research aims to compare four conservative treatments in patients aged 40 to 75 who experience shoulder pain affecting their sleep. The study also evaluates brain-derived neurotrophic factor BDNF and its precursor levels at various times after treatment to better understand their role in recovery and sleep improvement. Participants will be randomly assigned to one of four groups standardized rehabilitation alone rehabilitation plus a corticosteroid injection into the subacromial bursa rehabilitation plus a platelet-rich plasma PRP injection prepared from the patients blood or rehabilitation combined with a suprascapular nerve block using lidocaine. Each intervention targets pain relief, shoulder function, and sleep quality. Throughout the six-month study, participants will undergo assessments including shoulder strength and motion measurements, pain rating scales, sleep quality indexes, and BDNF protein and mRNA level evaluations. Additional tests like cognitive assessments and muscle imaging will also be performed. These evaluations will help determine which treatment best improves pain, function, and sleep for patients with supraspinatus tendon injuries.

Conservative Treatment in Patients With Supraspinatus Tendon Injury.