The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients

What this Trial Is About

Researchers are evaluating how well the continuous carotid doppler technique can track changes in cardiac output compared to the traditional thermodilution method in adult patients undergoing cardiac surgery. The study aims to understand if this noninvasive method can reliably estimate cardiac output and heart function, which may offer a simpler alternative to the invasive thermodilution technique currently considered the gold standard. The study involves cardiac surgery patients who are monitored using the thermodilution technique. Interventions include passive leg raising, where the patient is moved from a semi-recumbent to a supine position with legs elevated at 45 degrees, and dobutamine infusion to assess cardiac output changes. Measurements of cardiac output are taken using both thermodilution and continuous carotid doppler at specific times: 5 minutes after sedation, 2 minutes after passive leg raising, 15 minutes after stopping passive leg raising, and 30 minutes after starting dobutamine infusion. Participants will be monitored closely during the surgery and interventions, with cardiac output measured repeatedly to compare the two methods. The study focuses on tracking cardiac output changes as the primary outcome. Adult patients on mechanical ventilation with thermodilution monitoring are included, while those with severe heart conditions or mechanical circulatory support are excluded. The study is conducted at Shanghai Zhongshan Hospital and lasts through December 2026.

Consistency of Carotid Doppler Blood Flow and Thermodilution Technique