Actively Recruiting

Phase 2
Age: 18Years - 100Years
MALE
NCT05656794

Consolidative Prostate Radiotherapy in Metastatic Prostate Cancer

Led by University Health Network, Toronto · Updated on 2026-03-23

40

Participants Needed

1

Research Sites

416 weeks

Total Duration

On this page

Sponsors

U

University Health Network, Toronto

Lead Sponsor

T

TerSera Therapeutics LLC

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a prospective, randomized phase II trial investigating if radiation treatment delivered every other day for 2 weeks has the same side effects as radiation treatment delivered once weekly for 6 weeks.

CONDITIONS

Official Title

Consolidative Prostate Radiotherapy in Metastatic Prostate Cancer

Who Can Participate

Age: 18Years - 100Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically-proven prostate cancer
  • Presence of low-volume or high-volume metastases (high volume defined as the presence of visceral metastases or 6 bone lesions with at least 1 lesion beyond the vertebral bodies and pelvis)
  • Planned to or receiving systemic treatment ADT 1 ARAT as per physician discretion (Previous chemotherapy allowed if completed more than 6 weeks prior to randomization)
  • Planned for EBRT
  • ECOG performance status 0 or 1
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Prior radiotherapy to pelvis
  • Active ulcerative colitis or Crohn's Disease, at discretion of treating physician
  • Any condition where radiotherapy is contraindicated

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University Health Network, Princess Margaret Hospital

Toronto, Ontario, Canada, M5G 2M9

Actively Recruiting

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Research Team

P

Peter Chung, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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