Actively Recruiting

Age: 18Years +
All Genders
NCT03552926

Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2022-05-02

500

Participants Needed

1

Research Sites

481 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to determine in patients with a recent lacunar strokes (\<15 days), the natural history of cognitive disturbances and disability.

CONDITIONS

Official Title

Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years and above
  • History of recent (less than 15 days) neurological deficit related to a small subcortical infarct (evidenced by medical history or physical examination)
  • Diagnosis of recent small subcortical infarct on MRI (hyperintensity on diffusion-weighted imaging showing an infarction in the territory of one perforating artery) presumably responsible for the corresponding neurological deficit
  • Lesion diameter mess than 20 mm
  • Ability to comply with scheduled follow-up and annual neurological evaluation
  • Affiliation to the national French health insurance (sécurité sociale)
  • Signature of informed consent
Not Eligible

You will not qualify if you...

  • Prior diagnosis of dementia according to DSM IV criteria
  • Prior severe disability with Rankin scale ≥ 4
  • Serious concomitant systemic disorder that can compromise the follow-up study;
  • Leukoencephalopathy of non-vascular origin;
  • Severe psychiatric disorder;
  • Inability to obtain an informed signed consent from the patient or his/her family;
  • Medical contraindication or refusal to undergo cerebral magnetic resonance scanning (MRI).

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpital Lariboisière

Paris, France, 75010

Actively Recruiting

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Research Team

E

Eric JOUVENT, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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