Sex differences in primary Sjögren's disease: prognostic impact on mortality and cancer.
Chunxin Lei, Xiya Zhang, Yan Zhang...
https://pubmed.ncbi.nlm.nih.gov/41530868Actively Recruiting
Age: 18Years - 75Years
All Genders
ID06528197
Construction of Clinical Model of Primary Sjogren's Syndrome Combined Traditional Chinese Medicine and Western Medicine Based on Multi-omics
Led by China-Japan Friendship Hospital · Updated on 2024-07-30
1000
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
Sponsors
C
China-Japan Friendship Hospital
Lead Sponsor
X
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are creating a large group of patients diagnosed with primary Sjogren's syndrome to collect extensive biological data using multi-omics methods. The goal is to develop models for diagnosing the disease and predicting how it will progress. This observational study combines insights from both traditional Chinese and Western medicine to better understand the condition. Participants will be grouped based on their exposure status, but no specific drug or treatment is assigned since the study observes natural disease progression and related health outcomes. Data collection occurs at the start and again after six months to track system involvement, mortality, tumor occurrence, and connective tissue disease development in participants. During the study, patients will undergo evaluations at baseline and six months later. Researchers will gather clinical information and biological samples to analyze multiple health aspects. The study monitors participants' health outcomes over time without intervention, aiming to improve diagnostic and prognostic tools for primary Sjogren's syndrome. The trial is expected to run until the end of 2026.
CONDITIONS
Brief Title
Construction of Clinical Model of Primary Sjogren's Syndrome Combined Traditional Chinese and Western Medicine
Who Can Participate
Age: 18Years - 75Years
All Genders
Eligibility Criteria
You may qualify if you...
- Meets the 2002 AECG or 2016 ACR/EULAR classification criteria of primary Sjogren's syndrome
- Aged between 18 and 75 years
You will not qualify if you...
- Has other connective tissue diseases besides primary Sjogren's syndrome
- Women who are pregnant or breastfeeding
- Has severe cardiovascular or cerebrovascular disease, liver or kidney failure, or serious malignant tumors
- Any other condition considered unsuitable for enrollment by the investigators, such as cognitive impairment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Long-term Monitoring
Duration - 6 months
Participants are observed to track system involvement, mortality, tumor occurrence, and connective tissue disease over time.
Baseline visit and 1 follow-up visit at 6 months
Trial Site Locations
Total: 1 location
1
Jiaqi Chen
Beijing, Beijing Municipality, China, 100029
Actively Recruiting
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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