Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT07286058

Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

Led by Takeda · Updated on 2026-03-19

1182

Participants Needed

1

Research Sites

196 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Psoriatic arthritis (PsA) is a long-term inflammatory disease that affects the joints and skin. The purpose of this study is to check how safe zasocitinib is, how well it is tolerated and how well it works in adults with PsA over a longer period of time. Adults who completed the 1-year (52-week) treatment period in one of the parent studies (TAK-279-PsA-3001 \[NCT06671483\] or TAK-279-PsA-3002 \[NCT06671496\]) may be able to join this continuation study (also called long-term extension or LTE study). All participants in this continuation study, will receive zasocitinib (lower or higher dose), once a day (QD). Each participant can be in this study for approximately 2 years (108 weeks). This includes a treatment period of up to 2 years (104 weeks) and a 1-month (4-week) follow-up period to monitor a participant's health.

CONDITIONS

Official Title

Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant is 18 years or older (19 or older in South Korea) at consent
  • Completed 52-week treatment in parent study TAK-279-PsA-3001 or TAK-279-PsA-3002 without permanent discontinuation
  • Investigator believes participant may benefit from continued or newly started zasocitinib therapy
Not Eligible

You will not qualify if you...

  • Investigator deems participant not benefiting due to lack of improvement or worsening symptoms in parent study
  • Met criteria for permanent discontinuation in parent studies
  • Developed diseases confounding benefit evaluation, including rheumatoid arthritis, axial spondyloarthritis (excluding primary PsA with spondylitis), systemic lupus erythematosus, Lyme disease, gout, or fibromyalgia
  • Developed comorbid skin conditions interfering with study assessments such as non-plaque psoriasis types (erythrodermic, pustular, guttate, inverse, or drug-induced)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

First OC Dermatology Research Inc.

Fountain Valley, California, United States, 92708

Actively Recruiting

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Research Team

T

Takeda Contact

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis | DecenTrialz