Actively Recruiting

Phase Not Applicable
Age: 0 - 6Hours
All Genders
NCT06563687

Continuous Glucose Monitoring in HIE

Led by University of Campania Luigi Vanvitelli · Updated on 2024-08-21

70

Participants Needed

3

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is to examine whether the use of continuous glucose monitoring (CGM) to guide the clinical management of glycaemic control will result into an increased time in the target glucose concentration. To further examine the efficacy of using CGM the following secondary outcomes in the two groups were assessed: mean glucose values, glucose variability within individuals, percentage of time that glucose values are in hyperglycaemic or hypoglycaemic ranges. Randomized controlled trial recruiting neonates (Birth weight \>1.8kg, Gestation\>36 weeks) with moderate or severe hypoxic ischemic encephalopathy (HIE) following perinatal asphyxia . Neonates will be randomly assigned (1:1) within 6 hours of birth to receive either the intervention with real-time CGM or standard care for 72 hours.

CONDITIONS

Official Title

Continuous Glucose Monitoring in HIE

Who Can Participate

Age: 0 - 6Hours
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Birth weight >1.8kg
  • Gestation >35 weeks
  • Aged <6 hours
  • Moderate or severe hypoxic ischemic encephalopathy following perinatal asphyxia
Not Eligible

You will not qualify if you...

  • Major congenital malformations
  • Inborn errors of metabolism
  • Congenital infections
  • Imminent death

AI-Screening

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Trial Site Locations

Total: 3 locations

1

A.O.S.G. Moscati

Avellino, Italy, 83100

Not Yet Recruiting

2

University of Campania Luigi Vanvitelli

Naples, Italy, 80100

Actively Recruiting

3

Monaldi | | AORN - Ospedali dei ColliAORN - Ospedali dei Colli

Naples, Italy, 80131

Not Yet Recruiting

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Research Team

P

Paolo Montaldo, PhD

CONTACT

S

Simona Puzone, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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