Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT06310356

Continuous Glucose Monitoring for Women With Gestational Diabetes

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-05-05

386

Participants Needed

14

Research Sites

140 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

U

University Hospital, Antwerp

Collaborating Sponsor

AI-Summary

What this Trial Is About

There are a few ongoing large randomized controlled trials (RCT's) on continuous glucose monitoring (CGM) in women with gestational diabetes (GDM) powered for pregnancy outcomes. However, none of these studies included women diagnosed with early GDM. The CORDELIA trial is a Belgian open-label multi-centric RCT with 14 centers in women with GDM (including both early and late GDM). Women will be randomized 1/1 to either treatment with CGM (intervention group, Freestyle Libre 3) or continue with self-monitoring of blood glucose (SMBG) with glucometer in line with normal routine (control arm). The study ends at the postpartum oral glucose tolerance test (OGTT 6-24 weeks postpartum) to screen for glucose intolerance.

CONDITIONS

Official Title

Continuous Glucose Monitoring for Women With Gestational Diabetes

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years of age at the time of signing the Informed Consent Form (ICF)
  • Singleton pregnancy
  • Diagnosed with gestational diabetes before 29.6 weeks of pregnancy
  • Needs to be able to understand and speak Dutch, French or English
  • Have email access
Not Eligible

You will not qualify if you...

  • History of type 2 or type 1 diabetes, or presence of auto-immune antibodies for type 1 diabetes
  • Physical or psychological disease likely to interfere with the conduct of the study (based on the evaluation by the treating physician)
  • Use of medication with significant impact on glycemia (such as high dose glucocorticoids and diabetes medication such as metformin)
  • Participation in an interventional Trial with an investigational medicinal product or device
  • Multiple pregnancy
  • History of bariatric surgery
  • Known allergy to the adhesives used with the continuous glucose monitoring

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 14 locations

1

OLV Aalst-Asse

Aalst, Oost-Vlaanderen, Belgium, 9300

Actively Recruiting

2

UZA

Antwerp, Belgium

Actively Recruiting

3

ZNA Antwerpen

Antwerp, Belgium

Actively Recruiting

4

Imelda Bonheiden

Bonheiden, Belgium, 2820

Actively Recruiting

5

AZ St Jan Brugge

Bruges, Belgium, 8000

Actively Recruiting

6

Erasme

Brussels, Belgium

Actively Recruiting

7

UZ Gent

Ghent, Belgium, 9000

Actively Recruiting

8

AZ St Lucas Gent

Ghent, Belgium

Actively Recruiting

9

AZ Groeninge Kortrijk

Kortrijk, Belgium, 8510

Actively Recruiting

10

UZ Leuven

Leuven, Belgium

Actively Recruiting

11

CHU de Liège

Liège, Belgium

Actively Recruiting

12

AZ St Maarten Mechelen

Mechelen, Belgium

Actively Recruiting

13

AZ Oostende

Ostend, Belgium

Actively Recruiting

14

Vitaz

Sint-Niklaas, Belgium

Actively Recruiting

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Research Team

K

Katrien Benhalima, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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