Actively Recruiting
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
Led by Phoenix Children's Hospital · Updated on 2026-04-27
166
Participants Needed
1
Research Sites
300 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU. We intend to determine if the continuous infusion leads to a decreased utilization of opiates when compared to intermittent ketorolac.
CONDITIONS
Official Title
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 3 months to 4 years 11 months admitted postoperatively to the CVICU during the study period
- Study medication started within 12 to 24 hours after surgery
- Cardiovascular attending approves ketorolac use for pain control after reviewing surgery and labs
You will not qualify if you...
- Acute kidney injury as defined by pRIFLE criteria
- Allergy or sensitivity to ketorolac or any NSAID medications
- Need for mechanical circulatory support (ECMO) or continuous renal replacement therapy (CRRT) within 48 hours after surgery
- History of orthotopic heart transplantation
- Clinically significant bleeding
- Known preoperative renal disease, renal transplant history, or congenital/acquired renal abnormalities or deformities
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Phoenix Children's Hospital
Phoenix, Arizona, United States, 85016
Actively Recruiting
Research Team
K
Kevin Engelhardt, MD
CONTACT
S
Samantha Stack, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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