Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04882904

Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part.

Led by Centre Hospitalier Universitaire de Liege · Updated on 2025-12-05

45

Participants Needed

1

Research Sites

322 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Liege

Lead Sponsor

S

SYSNAV

Collaborating Sponsor

AI-Summary

What this Trial Is About

ActiSLA is a monocentric academic study. Patients with amyotrophic lateral sclerosis may be included on a voluntary basis. The investigators plan to include a group of approximately 20 patients with ALS. The investigators have planned to assess patient every three months for a year. On each visit, participants will undergo a clinical examination with MRC sum score and Ashworth scores. They will perform few tests ( 6-minutes walk test (6MWT), dynamometric measure, electromyography, Edinburgh Cognitive and Behavioural ALS Screen ) and will answer to some questionaires (dysphagia handicap scale, ALS-SFR-r). After each visit, participants will wear Actimyo for one month daily.

CONDITIONS

Official Title

Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically defined or probable diagnosis of ALS according to El Escorial criteria revised with Awaji's electro-diagnostic algorithm.
  • Age over 18 years.
  • Signed informed consent.
  • If on Riluzole treatment, dosage must be stable for at least 1 month and maintained during the study.
Not Eligible

You will not qualify if you...

  • Severe cognitive disorders or communication difficulties preventing understanding or data collection.
  • Any other past or present condition affecting motor function.
  • Surgery or trauma in upper or lower limbs within past 6 months.
  • Neurological, endocrine, infectious, allergic, or chronic/acute inflammatory condition within 3 weeks before inclusion.
  • Participation in another interventional clinical trial.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHR Citadelle

Liège, Liège, Belgium, 4000

Actively Recruiting

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Research Team

L

Laurie MEDARD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part. | DecenTrialz