The operation of the century: total hip replacement.
Ian D Learmonth, Claire Young, Cecil Rorabeck
https://pubmed.ncbi.nlm.nih.gov/17964352Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID06221709
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial Comparing Radiofrequency and Corticosteroid Injection
Led by University of Brasilia · Updated on 2024-01-24
70
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
Sponsors
U
University of Brasilia
Lead Sponsor
S
Sarah Network of Rehabilitation Hospitals
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating treatments for adults with symptomatic unilateral hip osteoarthritis, focusing on managing pain and improving function. This prospective, single-center, double-blinded, randomized clinical trial compares the effects of intraarticular corticosteroid injection alone versus combined with Conventional Radiofrequency (CRF) targeting the anterior sensory branches of the hip. The study aims to determine which approach better controls pain and enhances quality of life over 24 weeks. Participants will be randomly assigned to one of two groups. The control group receives an intraarticular injection of corticosteroid and anesthetic directly into the hip joint. The intervention group undergoes radiofrequency ablation targeting specific sensory nerves of the hip followed by the same corticosteroid and anesthetic injection as the control group. Procedures are done under sedation or general anesthesia with precise imaging guidance to ensure accurate treatment delivery. Throughout the study, participants will be assessed at baseline, 1 week, 12 weeks, and 24 weeks for pain levels, hip muscle strength, medication use, and overall satisfaction. Imaging and motor stimulation techniques ensure safety during nerve ablation. The main outcome measured is quality of life using the WOMAC questionnaire. Researchers will also monitor adverse effects. The total study duration for each participant is about 24 weeks.
CONDITIONS
Brief Title
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Individuals 18 years of age or older
- Symptomatic unilateral hip osteoarthritis, grades II and III by Kellgreen and Lawrance classification
- Hip pain present for more than six months in medial, anterior, anterolateral, or lateral regions
You will not qualify if you...
- Radiculopathy with ipsilateral radiation
- Osteonecrosis of the femoral head
- Previous hip arthroplasty or surgical scars altering hip anatomy
- High dislocation of the hip
- Pain only in the posterior hip region
- Symptomatic osteoarthritis of the ipsilateral knee
- Corticosteroid or hyaluronic acid injection in the hip within the last six months
- Neurological or psychiatric diseases
- Peripheral neuropathy
- Use of a pacemaker
- Prothrombin activity time (INR) greater than 3
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Single treatment visit with follow-up up to 24 weeks
Participants receive either radiofrequency ablation targeting hip sensory nerves followed by intraarticular infiltration of corticosteroid and anesthetic or intraarticular infiltration alone to manage hip osteoarthritis pain.
1 treatment visit and follow-up visits at 1 week, 12 weeks, and 24 weeks
Follow-up
Duration - 24 weeks ± 1 week
Participants are monitored for changes in pain, muscle strength, medication intake, satisfaction, and any adverse effects after treatment.
Visits at 1 week, 12 weeks, and 24 weeks post-treatment
Trial Site Locations
Total: 1 location
1
Rede Sarah Hospitais de Reabilitação
Brasília, Federal District, Brazil, 70335901
Actively Recruiting
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Research Team
G
Gilvan F Vaz, MD
J
João M Montecchi, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Prabjit Ajrawat, Lenny Radomski, Anuj Bhatia...
https://pubmed.ncbi.nlm.nih.gov/31578561Review of Knee Joint Innervation: Implications for Diagnostic Blocks and Radiofrequency Ablation.
Shannon L Roberts, Alison Stout, Paul Dreyfuss
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Michael Gofeld, Carlos E Restrepo-Garces, Brian R Theodore...
https://pubmed.ncbi.nlm.nih.gov/22554345Percutaneous radiofrequency lesioning of sensory branches of the obturator and femoral nerves for the treatment of hip joint pain.
M Kawaguchi, K Hashizume, T Iwata...
https://pubmed.ncbi.nlm.nih.gov/11707799