Clinically important improvement thresholds for Harris Hip Score and its ability to predict revision risk after primary total hip arthroplasty.
Jasvinder A Singh, Cathy Schleck, Scott Harmsen...
https://pubmed.ncbi.nlm.nih.gov/27286675/Actively Recruiting
Led by University of Brasilia · Updated on 2024-01-24
70
Participants Needed
1
Research Sites
34 weeks
Total Duration
Researchers are evaluating treatments for adults with symptomatic unilateral hip osteoarthritis, focusing on managing pain and improving function. This prospective, single-center, double-blinded, randomized clinical trial compares the effects of intraarticular corticosteroid injection alone versus combined with Conventional Radiofrequency CRF targeting the anterior sensory branches of the hip. The study aims to determine which approach better controls pain and enhances quality of life over 24 weeks. Participants will be randomly assigned to one of two groups. The control group receives an intraarticular injection of corticosteroid and anesthetic directly into the hip joint. The intervention group undergoes radiofrequency ablation targeting specific sensory nerves of the hip followed by the same corticosteroid and anesthetic injection as the control group. Procedures are done under sedation or general anesthesia with precise imaging guidance to ensure accurate treatment delivery. Throughout the study, participants will be assessed at baseline, 1 week, 12 weeks, and 24 weeks for pain levels, hip muscle strength, medication use, and overall satisfaction. Imaging and motor stimulation techniques ensure safety during nerve ablation. The main outcome measured is quality of life using the WOMAC questionnaire. Researchers will also monitor adverse effects. The total study duration for each participant is about 24 weeks.
CONDITIONS
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.
G
Gilvan F Vaz, MD
J
João M Montecchi, MD
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University of Brasilia
Lead Sponsor
Sarah Network of Rehabilitation Hospitals
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single treatment visit with follow-up up to 24 weeks
Participants receive either radiofrequency ablation targeting hip sensory nerves followed by intraarticular infiltration of corticosteroid and anesthetic or intraarticular infiltration alone to manage hip osteoarthritis pain.
1 treatment visit and follow-up visits at 1 week, 12 weeks, and 24 weeks
Duration - 24 weeks ± 1 week
Participants are monitored for changes in pain, muscle strength, medication intake, satisfaction, and any adverse effects after treatment.
Visits at 1 week, 12 weeks, and 24 weeks post-treatment
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Lead Sponsor
Sarah Network of Rehabilitation Hospitals
Collaborating Sponsor