Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06784882

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

Led by University of California, San Diego · Updated on 2025-06-17

40

Participants Needed

1

Research Sites

26 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor canal preoperatively. They will assess differences in pain (measured in numeric rating scale), opioid consumption, and physical therapy milestones from postoperative day 0 to 7.

CONDITIONS

Official Title

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult participants of at least 18 years of age
  • Undergoing a primary, unilateral, total knee arthroplasty
  • Planned single-injection adductor canal nerve block
  • Weight > 50 kg (to minimize the risk of local anesthetic toxicity)
Not Eligible

You will not qualify if you...

  • Chronic opioid or tramadol use: daily oxycodone equivalents > 20 mg for > 4 weeks
  • Neuro-muscular deficit of the surgical limb
  • Moderate pain (NRS > 3) in an anatomic location other than the surgical site
  • Planned hospital admission following surgery
  • History of opioid misuse
  • Those who lack capacity to complete informed consent
  • Inability to contact the investigators during the treatment period, and vice versa (e.g., lack of telephone access)
  • Incarceration
  • Pregnancy
  • Allergy to amide local anesthetics

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Diego

La Jolla, California, United States, 92037

Actively Recruiting

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Research Team

R

Rodney A Gabriel, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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