Actively Recruiting
Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury
Led by University of Washington · Updated on 2025-04-27
50
Participants Needed
1
Research Sites
206 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients with traumatic spinal cord injury (tSCI) often suffer from spinal cord swelling inside the thecal sac, which contains the spinal cord and surrounding fluid, leading to increased pressure on the spinal cord tissue and decreased spinal cord blood flow at the site of injury. The combination of increased pressure and decreased blood flow causes vascular hypoperfusion of the spinal cord and exacerbates the severity of injury. This is also referred to as secondary injury. Thus, knowledge of spinal cord hypoperfusion would allow the treating physician to optimize the hemodynamic condition of the patient with acute spinal cord injury and potentially improve functional outcomes.
CONDITIONS
Official Title
Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Acute spinal cord injury for less than 24 hours
- Injury severity ranging from mild with preserved motor function (AIS A) to complete loss of motor and sensory function below injury level (AIS D)
- Medically stable to undergo routine dorsal decompression, spinal realignment, and stabilizing with segmental instrumentation
You will not qualify if you...
- Younger than 18 years old
- Missing or intact lower extremity neurological exam
- Traumatic head injury with Glasgow Coma Scale score of 11 or lower
- Spinal cord injury below thoracic level 10 (caudal to T10)
- Known sensitivity to lipid microsphere or its components such as polyethylene glycol (PEG)
- History of anaphylactoid reactions to ultrasound contrast agents
- Known cardiopulmonary conditions
- Presence of cardiac shunt
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Washington Harborview Medical Center
Seattle, Washington, United States, 98104
Actively Recruiting
Research Team
A
Amy Anderson
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here