Actively Recruiting
Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study
Led by Nantes University Hospital · Updated on 2026-05-12
667
Participants Needed
18
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Small Bowel Obstruction (SBO) is a frequent pathology in the emergency department (ED). Diagnosis is currently based on abdominal CT scan (CT). Moreover, CT is warranted to determine the therapeutic strategy in patients with SBO which could include medical treatment; surgical intervention or both. However, CT is associated with drawbacks such as radiation exposure, increased cost and ED length-of-stay. In a prospective observational study, a SBO was excluded by CT in 45% \[95%CI: 37-53\] of patients. There is, thus, a need for improving the appropriateness of CT-scan for suspected SBO. A recent meta-analysis showed that Point of care ultrasound (POCUS) had a good diagnostic accuracy (sensitivity 83% \[95%CI 71.7%-90.4%\]), specificity 93% \[95%CI 55.3%-99.3%\]). Another meta-analysis found rather similar results (sensitivity 83% \[(95% CI 89.0% to 94.7%\], specificity 96,6% \[95% CI 88.4% to 99.1%\]). In order to improve the negative predictive value of POCUS for its implementation as a rule-out strategy, CHU of Nantes emergency unit studied the combination of POCUS with Gestalt pre-test probability of SBO determined by the emergency physician. This SBO probability classified the patients as low, moderate or high risk of SBO. In patients with low or moderate Gestalt probability, CHU of Nantes emergency unit found that this combined strategy had a sensitivity of 100% \[95% CI: 88-100\] and NPV 100% \[92-100%\]. By (i) focusing on patients with a low or moderate Gestalt clinical probability and (ii) increasing the number of patients included, CHU of Nantes emergency unit intends to demonstrate that POCUS is able to exclude SBO in this population. This would avoid unnecessary CT and thus lower costs, ED length-of-stay and hospital radiologists workload. A POCUS will be performed followed by a CT (gold standard). The main objective will be the ability of POCUS to rule-out SBO in patients with low or moderate Gestalt clinical probability.
CONDITIONS
Official Title
Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years, no upper age limit
- Admitted to the emergency department with suspected small bowel obstruction symptoms such as abdominal pain, vomiting, or cessation of gas and feces
- Low or moderate clinical Gestalt probability of small bowel obstruction
- Able to understand the study protocol and give agreement
- Oral non-opposition to participate in the study
You will not qualify if you...
- Under legal guardianship
- Pregnant women
- Nursing mothers
- Unable to speak or understand French
- Without health insurance
- Already had imaging confirming small bowel obstruction diagnosis
- Currently participating in any interventional study focused on abdominal pain before POCUS and CT are done
AI-Screening
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Trial Site Locations
Total: 18 locations
1
Chu Clermont-Ferrand Hopital Gabriel Montpied
Clermont-Ferrand, France, France, 63100
Actively Recruiting
2
Ghem Groupe Hospitalier Eaubonne Montmorency Simone Veil
Eaubonne, France, France, 95600
Actively Recruiting
3
CHD Vendée
La Roche-sur-Yon, France, France, 85925
Actively Recruiting
4
CHD Vendée, Luçon
Luçon, France, France, 85407
Actively Recruiting
5
Ap-Hm Hopital La Timone
Marseille, France, France, 13005
Actively Recruiting
6
Hôpital Nord
Marseille, France, France, 13015
Withdrawn
7
Ghsif Groupe Hospitalier Sud Ile de Franc _ Ch Melun
Melun, France, France, 77000
Actively Recruiting
8
CHD Vendée, Montaigu
Montaigu, France, France, 85600
Actively Recruiting
9
CHU Nantes
Nantes, France, France, 44000
Actively Recruiting
10
Le Confluent
Nantes, France, France, 44200
Actively Recruiting
11
CHU CAREMEAU - Nimes
Nîmes, France, France, 30029
Actively Recruiting
12
AP-HP Est Parisien _ ST-ANTOINE
Paris, France, France, 75012
Actively Recruiting
13
P-HP Paris Centre - COCHIN
Paris, France, France, 75014
Actively Recruiting
14
Chru Poitiers
Poitiers, France, France, 86021
Actively Recruiting
15
CH MEMORIAL - Saint Lô
Saint-Lô, France, France, 50009
Actively Recruiting
16
CH Saint-Nazaire
Saint-Nazaire, France, France, 44600
Actively Recruiting
17
Groupe Hospitalier Selestat Obernai (Ghso)
Sélestat, France, France, 67600
Actively Recruiting
18
Hopital PURPAN CHU Toulouse
Toulouse, France, France, 31300
Actively Recruiting
Research Team
P
Philippe LE CONTE Professor LE CONTE, Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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