Actively Recruiting

Age: 18Years +
All Genders
NCT06803628

Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study

Led by Nantes University Hospital · Updated on 2026-05-12

667

Participants Needed

18

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Small Bowel Obstruction (SBO) is a frequent pathology in the emergency department (ED). Diagnosis is currently based on abdominal CT scan (CT). Moreover, CT is warranted to determine the therapeutic strategy in patients with SBO which could include medical treatment; surgical intervention or both. However, CT is associated with drawbacks such as radiation exposure, increased cost and ED length-of-stay. In a prospective observational study, a SBO was excluded by CT in 45% \[95%CI: 37-53\] of patients. There is, thus, a need for improving the appropriateness of CT-scan for suspected SBO. A recent meta-analysis showed that Point of care ultrasound (POCUS) had a good diagnostic accuracy (sensitivity 83% \[95%CI 71.7%-90.4%\]), specificity 93% \[95%CI 55.3%-99.3%\]). Another meta-analysis found rather similar results (sensitivity 83% \[(95% CI 89.0% to 94.7%\], specificity 96,6% \[95% CI 88.4% to 99.1%\]). In order to improve the negative predictive value of POCUS for its implementation as a rule-out strategy, CHU of Nantes emergency unit studied the combination of POCUS with Gestalt pre-test probability of SBO determined by the emergency physician. This SBO probability classified the patients as low, moderate or high risk of SBO. In patients with low or moderate Gestalt probability, CHU of Nantes emergency unit found that this combined strategy had a sensitivity of 100% \[95% CI: 88-100\] and NPV 100% \[92-100%\]. By (i) focusing on patients with a low or moderate Gestalt clinical probability and (ii) increasing the number of patients included, CHU of Nantes emergency unit intends to demonstrate that POCUS is able to exclude SBO in this population. This would avoid unnecessary CT and thus lower costs, ED length-of-stay and hospital radiologists workload. A POCUS will be performed followed by a CT (gold standard). The main objective will be the ability of POCUS to rule-out SBO in patients with low or moderate Gestalt clinical probability.

CONDITIONS

Official Title

Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years, no upper age limit
  • Admitted to the emergency department with suspected small bowel obstruction symptoms such as abdominal pain, vomiting, or cessation of gas and feces
  • Low or moderate clinical Gestalt probability of small bowel obstruction
  • Able to understand the study protocol and give agreement
  • Oral non-opposition to participate in the study
Not Eligible

You will not qualify if you...

  • Under legal guardianship
  • Pregnant women
  • Nursing mothers
  • Unable to speak or understand French
  • Without health insurance
  • Already had imaging confirming small bowel obstruction diagnosis
  • Currently participating in any interventional study focused on abdominal pain before POCUS and CT are done

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 18 locations

1

Chu Clermont-Ferrand Hopital Gabriel Montpied

Clermont-Ferrand, France, France, 63100

Actively Recruiting

2

Ghem Groupe Hospitalier Eaubonne Montmorency Simone Veil

Eaubonne, France, France, 95600

Actively Recruiting

3

CHD Vendée

La Roche-sur-Yon, France, France, 85925

Actively Recruiting

4

CHD Vendée, Luçon

Luçon, France, France, 85407

Actively Recruiting

5

Ap-Hm Hopital La Timone

Marseille, France, France, 13005

Actively Recruiting

6

Hôpital Nord

Marseille, France, France, 13015

Withdrawn

7

Ghsif Groupe Hospitalier Sud Ile de Franc _ Ch Melun

Melun, France, France, 77000

Actively Recruiting

8

CHD Vendée, Montaigu

Montaigu, France, France, 85600

Actively Recruiting

9

CHU Nantes

Nantes, France, France, 44000

Actively Recruiting

10

Le Confluent

Nantes, France, France, 44200

Actively Recruiting

11

CHU CAREMEAU - Nimes

Nîmes, France, France, 30029

Actively Recruiting

12

AP-HP Est Parisien _ ST-ANTOINE

Paris, France, France, 75012

Actively Recruiting

13

P-HP Paris Centre - COCHIN

Paris, France, France, 75014

Actively Recruiting

14

Chru Poitiers

Poitiers, France, France, 86021

Actively Recruiting

15

CH MEMORIAL - Saint Lô

Saint-Lô, France, France, 50009

Actively Recruiting

16

CH Saint-Nazaire

Saint-Nazaire, France, France, 44600

Actively Recruiting

17

Groupe Hospitalier Selestat Obernai (Ghso)

Sélestat, France, France, 67600

Actively Recruiting

18

Hopital PURPAN CHU Toulouse

Toulouse, France, France, 31300

Actively Recruiting

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Research Team

P

Philippe LE CONTE Professor LE CONTE, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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