Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06138977

Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs

Led by University of Michigan · Updated on 2026-02-13

40

Participants Needed

1

Research Sites

216 weeks

Total Duration

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AI-Summary

What this Trial Is About

The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses. The central hypothesis of this project is that variable joint impedance can be parameterized by a continuous model based on measurable quantities called phase and task variables. This project will use machine learning to identify variable impedance functions from able-bodied data including joint perturbation responses across the phase/task space to bias the solution toward biological values.

CONDITIONS

Official Title

Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able-bodied participants aged between 18 to 65 years
  • Amputee participants aged between 18 to 70 years
  • Amputee participants weigh less than 250 lbs
  • Amputee participants must be more than two months post independent ambulation with transfemoral amputation
  • Amputee participants classified as K2, K3, or K4 ambulators and able to walk without assistive devices beyond their prosthesis
Not Eligible

You will not qualify if you...

  • Pregnant participants (self-report)
  • Any significant neuromuscular or musculoskeletal disorder interfering with the study
  • Unable to walk for 20 minutes
  • History of cardiovascular, vestibular, or visual diseases or impairments that interfere with the study
  • Cognitive deficits impairing informed consent or ability to follow instructions
  • Known allergy to medical grade tape
  • Amputee participants weighing over 250 pounds
  • Excessively long residual limb length or non-removable cosmetic cover preventing proper prosthesis fitting
  • Co-morbidities interfering with the study such as pacemaker placement, severe ischemia, or cardiac disease
  • Adults unable to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rehab Lab, University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

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Research Team

E

Emily Klinkman, MS

CONTACT

R

Robert D Gregg, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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