Actively Recruiting
Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
Led by Barts & The London NHS Trust · Updated on 2025-05-13
48
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
Sponsors
B
Barts & The London NHS Trust
Lead Sponsor
A
AtriCure, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).
CONDITIONS
Official Title
Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years and less than 80 years
- Persistent atrial fibrillation lasting more than 1 year
- Left atrium size less than 6 cm
- Ability to provide written informed consent
You will not qualify if you...
- Currently enrolled in another investigational study except observational registries without treatments
- Reversible or transient atrial fibrillation
- Absence of left atrial appendage or previous surgical ligation of left atrial appendage
- Previous cardiac or abdominal surgery
- Contraindication to anticoagulation
- Hypertrophic cardiomyopathy
- Significant valve disease
- Previous catheter or surgical ablation for atrial fibrillation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
St Bartholomew's Hospital
London, United Kingdom, EC1A 4AS
Actively Recruiting
Research Team
S
Syed Ahsan
CONTACT
S
Shahana Hussain
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here