Actively Recruiting

Age: 18Years +
All Genders
NCT05972343

COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

Led by Washington University School of Medicine · Updated on 2026-05-07

100

Participants Needed

1

Research Sites

418 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a subject registry study of patients who undergo cryoablation for their breast cancer after being determined not to be surgical candidates. Data collected as part of this registry will be used to assess the safety of percutaneous ultrasound-guided cryoablation in this population as well as provide long-term follow-up of subjects who received cryoablation.

CONDITIONS

Official Title

COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of breast cancer
  • Breast cancer mass must be visible on ultrasound and more than 5 mm from the skin
  • Not undergoing surgery due to medical conditions preventing sedation or anesthesia
  • Not undergoing surgery because disease is unresectable and/or metastatic
  • Not undergoing surgery for other clinical reasons
  • Patient declines surgery
  • At least 18 years old
  • Able to understand and willing to sign an IRB-approved informed consent document
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

H

Heather Garrett, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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