Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07298213

Corazones Unidos Study

Led by University of Arizona · Updated on 2025-12-23

45

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

CVD is the leading cause of death among individuals with MASLD, a risk factor for liver cancer. In Southern Arizona, CVD and cancer (including liver and gastric cancer) are among the leading causes of death for Mexican-origin adults.1 Given Mexican-origin adults' disproportionate burden of CVD-related mortality37 and higher rates of MASLD compared to other ethnic/racial groups; we urgently need to develop contextually tailored strategies for management of CVD risk factors and outcomes. Thus, the purpose of this study is to examine the acceptability and feasibility of a community health worker (CHW)-led intervention aimed to increase cardiovascular risk awareness and promote lifestyle modifications among Mexican-origin adults with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in the Southern Arizona region. The proposed project has the potential to improve health outcomes for this vulnerable population and contribute to the ACS-CHERC's overarching goal of improving health equity for Hispanic communities and family caregivers.

CONDITIONS

Official Title

Corazones Unidos Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be Mexican-origin or of Mexican descent
  • Be 18 years of age or older
  • Have a confirmed MASLD diagnosis (CAP score of 248 dB/m or higher)
  • Have an adult member of your social network within 25 miles interested in participating
  • Be able to provide informed consent
  • Be able to speak, read, and write English and/or Spanish
  • Social support participants must be 18 or older
  • Social support participants must be a first-degree blood relative or spouse/significant other
  • Social support participants must be able to provide informed consent
  • Social support participants must be able to speak, read, and write English and/or Spanish
Not Eligible

You will not qualify if you...

  • Ongoing or recent alcohol consumption exceeding 21 standard drinks per week for men or 14 for women
  • Previous diagnosis of liver cancer
  • Regular use of anti-inflammatory or liver-toxic medications
  • Taking medication for psychiatric disorders
  • Diagnosis of depression
  • Diagnosis of autoimmune disorders
  • Women who are pregnant or breastfeeding
  • Social support participants living more than 25 miles from the intervention participant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UA Collaboratory for Metabolic Disease Prevention & Treatment

Tucson, Arizona, United States, 85714

Actively Recruiting

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Research Team

A

Adriana Maldonado Assistant Professor, PhD

CONTACT

E

Edgar Villavicencio A Research Coordinator, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Corazones Unidos Study | DecenTrialz