Actively Recruiting
Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
Led by Centre hospitalier de l'Université de Montréal (CHUM) · Updated on 2026-04-28
40
Participants Needed
1
Research Sites
573 weeks
Total Duration
On this page
Sponsors
C
Centre hospitalier de l'Université de Montréal (CHUM)
Lead Sponsor
M
Maisonneuve-Rosemont Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to demonstrate the safety and efficacy of the corneal collagen crosslinking with riboflavin and ultraviolet A in aim to increase the resistance of the graft used as a support for the Boston keratoprosthesis (KPro) type I against corneal melting (keratolysis or sterile necrosis).
CONDITIONS
Official Title
Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Candidate for KPro type I
- Ability to provide written consent
- Ability to attend all follow-up visits during the study
You will not qualify if you...
- Currently participating in another interventional study
- Unable to wear a therapeutic contact lens due to eyelid abnormalities
- Unable to provide written consent
- Severe dryness with keratinization of the ocular surface
- Presence of intraocular tumor
- Terminal glaucoma
- Inoperable retinal detachment
- Phthisis bulbi
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre Hospitalier de l'Université de Montréal
Montreal, Quebec, Canada, H2X3E4
Actively Recruiting
Research Team
M
Marie-Catherine Tessier
CONTACT
S
Soumaya Bouhout
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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