Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT03504956

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Led by Cedars-Sinai Medical Center · Updated on 2025-08-14

150

Participants Needed

1

Research Sites

439 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study proposes to develop an MRI technique named Coronary Atherosclerosis T1-weighed Characterization (CATCH) that will improve the quality and reliability of coronary atherosclerosis evaluation, as well as simplify the scanning process and significantly shorten imaging time compared with conventional imaging methods.

CONDITIONS

Official Title

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy volunteers aged 18 or older, male or female, with a BMI less than 30 and no history of cardiovascular disease
  • Medically stable patients aged 18 or older, male or female, suspected of or diagnosed with coronary artery disease who have not undergone stenting or bypass surgery
Not Eligible

You will not qualify if you...

  • Contraindications to MRI including mechanical, magnetic, or electrical implants, ferromagnetic implants, or ferromagnetic foreign bodies
  • Pregnancy
  • Inability to tolerate MRI due to inability to hold breath or claustrophobia
  • Non-compliance with study visit or procedure instructions
  • Severe allergy to animal dander or animal-instigated asthma
  • For gadolinium contrast use: renal function below required standards (GFR <45 ml/min) or previous allergic reaction to gadolinium-based contrast agents
  • Volunteers who have had four or more prior gadolinium contrast scans

AI-Screening

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Trial Site Locations

Total: 1 location

1

Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048

Actively Recruiting

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Research Team

R

Rosalia (Sally) A De Leon

CONTACT

D

Debiao Li, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

2

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