Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04748237

Coronary Computed Tomographic Angiography in Intermediate-risk Chest Pain Patients

Led by Karolinska Institutet · Updated on 2024-08-20

1600

Participants Needed

1

Research Sites

253 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim is to determine whether a diagnostic strategy including early coronary computed tomographic angiography in intermediate-risk patients presenting to the Emergency Department with chest pain reduces the composite endpoint of death, readmission because of myocardial infarction or unstable angina requiring revascularization.

CONDITIONS

Official Title

Coronary Computed Tomographic Angiography in Intermediate-risk Chest Pain Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Presentation to the Emergency Department within 24 hours with chest pain or symptoms suggestive of coronary artery disease
  • HEART-score greater than 3
  • Written informed consent given
Not Eligible

You will not qualify if you...

  • Any condition that could affect ability to follow the study protocol
  • Acute myocardial infarction
  • Known obstructive coronary artery disease over 50% or previous PCI or CABG
  • Clear alternative diagnosis for symptoms
  • Estimated glomerular filtration rate below 30 ml/min/1.73m2
  • Major allergy to iodinated contrast media
  • Conditions making high quality imaging unlikely
  • Not a Swedish resident with a personal ID number
  • Pregnancy or breastfeeding
  • Limited life expectancy, quality of life, or function making further CAD investigation not indicated
  • Prior participation in this trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Danderyd Hospital

Stockholm, Sweden, 18288

Actively Recruiting

Loading map...

Research Team

L

Liselotte Persson, RN

CONTACT

H

Henrik Löfmark, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here