Comparing CT Coronary Angiography and Invasive Angiography for Patients With Non-ST Elevation Acute Coronary Syndrome A Randomized Study of Team-Based Treatment Planning Using Non-Invasive CT Imaging

What this Trial Is About

Researchers are investigating whether coronary computed tomography angiography CCTA can be used instead of invasive coronary angiography ICA for people with non-ST-segment elevation acute coronary syndrome NSTEACS. This study aims to see if CCTA can safely and effectively guide treatment decisions, potentially reducing complications, improving comfort, speeding up care, and lowering costs compared to the traditional invasive approach. The trial is randomized and evaluates outcomes in individuals suspected of having this heart condition. Participants are assigned to one of two groups one group receives CCTA plus team-based interventional triage, where a specialized team reviews the CCTA results to plan treatment the other group receives the standard conventional ICA. Both procedures occur during hospital admission. The study monitors participants over time to compare these diagnostic and treatment strategies. During the study, researchers will track major heart-related events over one year, including heart attacks, death from cardiovascular causes, and need for unplanned procedures. They will also evaluate quality of life, angina symptoms, radiation exposure during hospital stay, and length of hospitalization. Participants provide informed consent and receive follow-up assessments to measure these outcomes and ensure safety throughout the trial.

Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome