Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05824520

Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-02-02

1066

Participants Needed

1

Research Sites

418 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The overall purpose of ACCURATE II trial is to compare the clinical outcomes of CT-derived FFR guided strategy versus medical therapy in patients with chronic coronary syndrome.

CONDITIONS

Official Title

Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older with at least one vessel having CT-derived FFR 0.80 or less
  • Diagnosis of chronic coronary syndromes
  • Signed written informed consent
Not Eligible

You will not qualify if you...

  • Known allergy or contraindication to Heparin, Aspirin, Clopidogrel, Prasugrel, Ticagrelor, or contrast media (except patients with manageable contrast media sensitivity)
  • Previous percutaneous coronary intervention or coronary artery bypass grafting
  • Sinus arrhythmia, cardiogenic shock, or severe heart failure (NYHA class III or higher)
  • Unable or unwilling to undergo CT scan or coronary angiography
  • On hemodialysis or have severe liver or kidney failure
  • Left main coronary artery stenosis 50% or greater
  • Complete blockage of target vessel
  • Pregnant or planning pregnancy during the trial
  • Life expectancy less than 2 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China, 310009

Actively Recruiting

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Research Team

J

Jian'an Wang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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