Actively Recruiting

Phase 4
Age: 18Years - 75Years
All Genders
NCT05858645

Correction of Psoriatic T Cell Signatures by Deucravacitinib

Led by University of California, San Francisco · Updated on 2024-06-27

25

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

B

Bristol-Myers Squibb

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to assess cutaneous and blood immune cell function of patients with psoriasis before and after initiation of treatment with the Tyrosine kinase 2 (TYK2) blocker, deucravacitinib.

CONDITIONS

Official Title

Correction of Psoriatic T Cell Signatures by Deucravacitinib

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Diagnosis of moderate to severe psoriasis with body surface area equal to or greater than 10%, PASI score equal to or greater than 12, and static Physician's Global Assessment of 3 or above
Not Eligible

You will not qualify if you...

  • Use of systemic immunosuppressive drugs within the last 12 weeks
  • Pregnancy
  • Severe immunodeficiency from genetic or infectious causes
  • Active tuberculosis or other serious infections
  • Active systemic cancer
  • Breastfeeding
  • Any condition or abnormality that may compromise safety or data quality as determined by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Francisco

San Francisco, California, United States, 94115

Actively Recruiting

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Research Team

R

Raymond Cho, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Correction of Psoriatic T Cell Signatures by Deucravacitinib | DecenTrialz