Actively Recruiting

Age: 18Years +
All Genders
NCT07555041

Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients

Led by Hospices Civils de Lyon · Updated on 2026-05-01

250

Participants Needed

2

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients. CRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure. Although CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability. The perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport. Because PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.

CONDITIONS

Official Title

Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patient
  • Admission within the previous 24 hours, or within 24 hours of the onset of a hemodynamic instability criterion (requirement for vasopressors or fluid resuscitation)
  • Absence of patient objection
Not Eligible

You will not qualify if you...

  • Legal guardianship, curatorship, or judicial protection
  • No social security coverage
  • Morphological abnormalities preventing CRT and IP measurements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Service de Réanimation cardio-vasculaire et thoracique, Hôpital Cardiologique louis Pradel, Hospices Civils de Lyon

Bron, France, 69500

Actively Recruiting

2

Service de Médecine Intensive-Réanimation, Hôpital Édouard Herriot, Hospices Civils de Lyon

Lyon, France, 69003

Actively Recruiting

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Research Team

N

Neven STEVIC, MD

CONTACT

M

Martin COUR, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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