Actively Recruiting
Correlation Between Capillary Refilling Time and Perfusion Index in Critically Ill Patients
Led by Hospices Civils de Lyon · Updated on 2026-05-01
250
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the relationship between capillary refill time (CRT) and perfusion index (PI) in critically ill patients to improve tissue perfusion monitoring. CRT is a standard method involving pressing the skin to observe color return time, but it is not standardized and can be time-consuming. The trial aims to find a more precise and efficient way to monitor tissue perfusion by comparing CRT with PI, which is automatically measured by a pulse oximetry sensor worn continuously on the finger. The study involves observing patients using two monitoring methods: CRT measurements performed manually and continuous automatic PI measurements. These methods will be compared to establish a correlation between the two indicators. The research takes place during the patient's admission and early management of hemodynamic instability. No additional treatments or interventions are given, as this is an observational study. Participants will be adults admitted within 24 hours or experiencing hemodynamic instability requiring support. Researchers will measure CRT and PI to determine the PI threshold linked to abnormal CRT. The study requires no extra procedures beyond these assessments and monitoring, with participant involvement focused on data collection during routine care. The study is scheduled to run until May 2027.
CONDITIONS
Brief Title
Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient
- Admission within the previous 24 hours, or within 24 hours of the onset of a hemodynamic instability criterion (requirement for vasopressors or fluid resuscitation)
- Absence of patient objection
You will not qualify if you...
- Legal guardianship, curatorship, or judicial protection
- No social security coverage
- Morphological abnormalities preventing CRT and IP measurements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At inclusion
Participants undergo microcirculation monitoring through Capillary Refill Time (CRT) and Perfusion Index (PI) measurements to assess their condition.
1 visit (in-person)
Duration - Up to 2 years until study completion
Participants are observed for changes in perfusion and microcirculation parameters over time without receiving active treatment.
Visits as per routine care or clinical need
Trial Site Locations
Total: 2 locations
1
Service de Réanimation cardio-vasculaire et thoracique, Hôpital Cardiologique louis Pradel, Hospices Civils de Lyon
Bron, France, 69500
Actively Recruiting
2
Service de Médecine Intensive-Réanimation, Hôpital Édouard Herriot, Hospices Civils de Lyon
Lyon, France, 69003
Actively Recruiting
Research Team
N
Neven STEVIC, MD
M
Martin COUR, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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