Actively Recruiting
The Correlation Between Circulatory Tumor Cells and Venous Thrombosis
Led by Chang Gung Memorial Hospital · Updated on 2025-09-24
120
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Research indicates a strong correlation between cancer and thrombosis, with approximately 20% of blood clots in the U.S. being cancer-related, according to CDC data. Cancer patients face a 4-7 times higher risk of thrombosis compared to non-cancer individuals. Certain cancer treatments, such as chemotherapy and targeted therapy, elevate the likelihood of venous thromboembolism (VTE). Cancer patients with VTE exhibit a significantly higher hazard ratio (H.R.) of 3.4 compared to those without VTE. This study aims to explore three main topics: (1) Comparing the differences and similarities of leukocyte populations between cancer-associated thrombosis (CAT) and venous thromboembolism (VTE). (2) Characterizing the factors contributing to increased incidence of cancer-associated thrombosis (CAT), with the hypothesis that circulating tumor microemboli (CTM) may express more thrombosis-related proteins than CTCs. (3) Understanding the effects of aspirin or NOACs on cancer-associated thrombosis and CTM formation.
CONDITIONS
Official Title
The Correlation Between Circulatory Tumor Cells and Venous Thrombosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Participants without cancer must have no history of cancer in the past five years
- Participants with cancer must have pathology confirming a malignant tumor
- Patients who have undergone catheter-based thrombectomy
- Agree to undergo thrombectomy procedure
You will not qualify if you...
- Participants without cancer who are in shock
- Participants without cancer who have severe sepsis
- Participants with cancer who are in shock
- Participants with cancer who have severe sepsis
- Participants with cancer diagnosed within the past five years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
New Taipei City TuCheng Hospital
New Taipei City, Taiwan
Actively Recruiting
Research Team
H
Hsin-Fu Lee, PhD
CONTACT
C
Chia-Hsun Hsieh, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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