Actively Recruiting

Age: 50Years - 85Years
All Genders
Healthy Volunteers
NCT05715710

Correlation Between Deep Medullary Veins and Cognitive Dysfunction in Cerebral Small Vessel Disease

Led by Zigong No.1 Peoples Hospital · Updated on 2025-01-28

200

Participants Needed

1

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to obtain the characteristics of cognitive impairment and imaging characteristics of patients with Cerebral small vessel disease (CSVD) through comprehensive and standardized neuropsychological assessment and multimodal imaging examination. The focus is to obtain the characteristics of cognitive impairment and imaging characteristics of patients with CSVD through 3.0T MRI SWI sequence. deep medullary veins (DMVs) were measured. To compare the demographic data, hematological indexes, imaging scores and the number of DMVs between CSVD groups with and without cognitive impairment, and to explore the correlation between deep medullary veins and cognitive dysfunction in cerebral small vessel disease.

CONDITIONS

Official Title

Correlation Between Deep Medullary Veins and Cognitive Dysfunction in Cerebral Small Vessel Disease

Who Can Participate

Age: 50Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 to 85 years old
  • Diagnosis of cerebral small vessel disease based on the 2015 Chinese Consensus and 2013 International Standards for imaging features
  • No large vessel stenosis over 50% after head and neck vascular examination
  • Stable vital signs and ability to cooperate with examinations
  • Signed informed consent by patient or legal representative
Not Eligible

You will not qualify if you...

  • Cerebral infarction or hemorrhage caused by large vessel disease or stenosis over 50%
  • Secondary white matter lesions from poisoning, inflammation, tumor, or other pathological causes
  • Cognitive or gait impairment due to other diseases like Alzheimer's, Parkinson's, or depression
  • Contraindications for MRI examination
  • Illiteracy or inability to cooperate with cognitive assessment due to severe hearing or visual impairment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zigong First People's Hospital

Zigong, Sichuan, China, 643000

Actively Recruiting

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Research Team

Y

ya x Xu

CONTACT

L

ling zhao

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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