Actively Recruiting
Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Patients
Led by University of Louisville · Updated on 2025-05-30
25
Participants Needed
1
Research Sites
84 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this clinical research project is to employ Mespere LifeSciences NeurOs Cerebral Oximetry system, equipped with noninvasive sensors approved by the FDA, to monitor and investigate the correlation within a cohort of patients suffering from traumatic brain injury (TBI), stroke, brain tumor, and brain bleeding. This study aims to investigate and establish the correlation between blood vessel functionality parameters-specifically, Vasodilation/Constriction Index (VDC), Vascular Resistance Index (VR), and Volume Reactivity Index (VRx)-with the crucial physiological indicators, Intracranial Pressure (ICP) and Mean Arterial Pressure (MAP). By doing so, the investigators seek to address fundamental questions surrounding cerebral hemodynamics and autoregulation in various neurological conditions.
CONDITIONS
Official Title
Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (over 18 years of age)
- Able and willing to provide written informed consent by self or legally authorized representative
- Clinical diagnosis of traumatic brain injury, brain hemorrhage, brain tumor, neurotrauma, hemorrhage, or stroke
- Continuous blood pressure monitoring via arterial line during the study
- Intracranial pressure monitoring in place during the study
You will not qualify if you...
- Increased risk due to study participation as determined by investigator (e.g., hemodynamic instability)
- Pregnant as determined by site standard practice
- Previous participation in this study or enrollment in interfering research studies
- Require or expected to require emergent medical care that could be delayed by study participation
- Allergy to adhesive tape
- Undergoing photodynamic therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Louisville Health
Louisville, Kentucky, United States, 40202
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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