Actively Recruiting
The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients with Advanced GISTs
Led by First Affiliated Hospital, Sun Yat-Sen University · Updated on 2025-02-26
60
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective, single-center, observational study to explore the correlation between ripretinib exposure and the efficacy and safety in patients with advanced gastrointestinal stromal tumors
CONDITIONS
Official Title
The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients with Advanced GISTs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who are aged ≥ 18 years.
- Gastrointestinal stromal tumors confirmed by histopathological examination, and CD117 and/or DOG-1-positive by immunohistochemistry.
- patients who are currently receiving Ripretinib treatment.
- Subjects must have at least one measurable lesion based on mRECIST v1.1 criteria, and have undergone at least one radiographic evaluation for efficacy analysis.
- Patients with an Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0 to 4
- Patient informed consent and signed written consent form.
- The patient was compliant and voluntarily scheduled for follow-up, treatment, laboratory tests, and other study procedures.
You will not qualify if you...
- Unable to complete at least 15 consecutive days of Ripretinib due to intolerance or disease progression.
- Individuals with other serious acute or chronic physical or mental health problems, or abnormal laboratory test results that increase the risk associated with participation in the study or use of the drug, or that could interfere with the interpretation of study results, and who, in the opinion of the investigator, are not suitable for participation in the study.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, China, 510080
Actively Recruiting
Research Team
X
xinhua zhang, MD
CONTACT
Y
yanzhe xia, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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