Study of Ultrasound Measurement of Quadriceps Muscle Compared to Whole-body Muscle Scan in Adults Recovering From Cancer

What this Trial Is About

This research focuses on adults who have had cancer and are now in remission or considered cured. It aims to study the effects of cancer and its treatments on muscles, particularly looking at muscle loss known as sarcopenia, which is common after cancer. The study also evaluates the use of ultrasound as a tool to detect muscle loss, alongside standard assessments like blood tests and muscle function tests. This work is part of a larger effort to improve quality of life and limit long-term side effects faced by cancer survivors. Participants in the study undergo a dedicated post-cancer assessment day, including standard organic measurements such as blood sugar, kidney and liver tests, and blood counts. In addition, an ultrasound examination of the thigh measures the size of the quadriceps muscle at five different points. The study also collects blood samples to analyze muscle-related biological markers. This non-interventional research is conducted under close medical supervision without altering participants standard care. Throughout the study, researchers analyze the relationship between muscle thickness measured by ultrasound and muscle mass measured by whole-body densitometry DEXA. They also explore correlations with muscle scans, functional tests, and biological markers over approximately nine years. Muscle ultrasound reproducibility is tested within a subgroup of participants. The study involves regular evaluations to better understand muscle health after cancer and to support patients in their recovery journey.

Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)