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Study of Metal Elements and Their Role in Radiation-Induced Oral Mucositis in Patients with Head and Neck Tumors Undergoing Radiotherapy
Led by Nanfang Hospital, Southern Medical University · Updated on 2025-05-13
383
Participants Needed
1
Research Sites
12 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are exploring the relationship between metal elements and the development of radiation-induced oral mucositis RIOM in patients treated for head and neck tumors, such as nasopharyngeal carcinoma. This observational study aims to understand how metal levels may predict the occurrence and severity of RIOM, a common and painful side effect of radiotherapy that significantly affects patients quality of life and treatment success. The study will follow patients who are undergoing radiotherapy for head and neck tumors. It will observe changes in metal elements over time and analyze how these changes relate to severe RIOM. The research does not involve experimental treatments but focuses on collecting data throughout the radiotherapy process and after, with a monitoring period lasting up to one year. Participants will be regularly assessed for the incidence and duration of severe oral mucositis, quality of life, and other radiation-related side effects. The study will include laboratory tests and clinical evaluations to monitor these outcomes. The total observation period for each participant can last up to one year following radiotherapy, allowing a comprehensive review of RIOM and its possible predictors.
CONDITIONS
Brief Title
Correlation and Predictive Research of Metal Elements in Radiation-Induced Oral Mucositis
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