Actively Recruiting
Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy
Led by Jessa Hospital · Updated on 2021-08-25
40
Participants Needed
1
Research Sites
373 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH. These lesions are believed to present at more advanced stages of the hearing and vestibular deterioration. Since then, other authors have described similar lesions in advanced non-genetic hearing and vestibular impairment as well. The purpose of this study is therefore to assess the radiologic investigation using CT and MR imaging of temporal bone to all subjects presenting with bilateral vestibulopathy, using the Barany criteria, compared to the p.P51S population.
CONDITIONS
Official Title
Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must meet the Barany criteria for bilateral vestibulopathy including one or more of: bilaterally pathological horizontal angular VOR gain less than 0.6 measured by video-HIT or scleral-coil technique, reduced caloric response (sum of bithermal max. peak SPV on each side less than 6 degrees/sec), or reduced horizontal angular VOR gain less than 0.1 upon sinusoidal stimulation on a rotatory chair with phase lead over 68 degrees
- Must be 18 years of age or older
You will not qualify if you...
- Younger than 18 years
- Does not meet Barany criteria for bilateral vestibulopathy
- Has contraindications for CT or MR imaging
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Jessa Hospital
Hasselt, Limburg, Belgium, 3500
Actively Recruiting
Research Team
S
sebastien p JanssensdeVarebeke, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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