Actively Recruiting
Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)
Led by University Hospital of Patras · Updated on 2025-12-05
100
Participants Needed
1
Research Sites
131 weeks
Total Duration
On this page
Sponsors
U
University Hospital of Patras
Lead Sponsor
U
University General Hospital of Heraklion
Collaborating Sponsor
AI-Summary
What this Trial Is About
The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy. Its primary objective is to investigate whether the presence of a specific echocardiographic contraction pattern before implantation is associated with increased rates of acute improvement in myocardial function (as measured by an ultrasound) and to compare the improvement in two groups of patients based on the type of pacing (biventricular or left-sided pacing)
CONDITIONS
Official Title
Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years and under 90 years
- Patients needing resynchronization therapy due to symptoms despite optimal medication
- Heart failure with reduced ejection fraction (EF below 35%)
- Complete left bundle branch block (LBBB) with specific ECG criteria
- Intraventricular septum diameter greater than 8 mm
- Written informed consent given
You will not qualify if you...
- Right bundle branch block (RBBB) or atypical LBBB QRS patterns
- Patients who already have a pacemaker or ICD and are eligible for upgrade
- Patients with hypertrophic cardiomyopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Patras
Pátrai, Greece, Greece, 26504
Actively Recruiting
Research Team
G
Georgios Leventopoulos, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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