Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT02346396

Cortical Stimulation by Direct Current for the Treatment of Chronic Pain : Pilot-study of a Stimulation Device at Home

Led by Hospices Civils de Lyon · Updated on 2024-01-02

40

Participants Needed

1

Research Sites

638 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to confirm the analgesic effect of tDCS in neuropathic chronic pain, to estimate the importance and the duration of this effect, and to improve its efficiency by the use at home. It is established that the repetition of the sessions of cortical stimulation over a week improves their analgesic efficacy. However, this effect does not exceed a few weeks and is much lower than that of the stimulation implanted surgically. Implanted stimulation operates periodically, several times a day, and this "repetition of doses ", akin to the regular taking of a medicine, may explain its longer efficacy for pain relief which, may extend over several years (André-Obadia and al 2014). No study at this date has estimated the long-term effect of non-invasive stimulation when is also periodically repeated on a daily basis, over several weeks.

CONDITIONS

Official Title

Cortical Stimulation by Direct Current for the Treatment of Chronic Pain : Pilot-study of a Stimulation Device at Home

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 to 80 years, men or women, with chronic neuropathic pain lasting more than one year that is resistant to medication
  • Pain score greater than 2 during the baseline week
  • Stable pain medication for at least one month
  • Patients whose doctors are considering non-drug treatments and presurgical evaluation
  • Patients with an operational internet connection who or whose caregiver can access the remote stimulation system
  • Patients with social security coverage
  • Patients who have given written consent
Not Eligible

You will not qualify if you...

  • History of drug addiction
  • History of epilepsy
  • Presence of intracranial ferromagnetic equipment or implanted stimulation devices (such as pacemakers or nerve stimulators)
  • Started a new pain medication less than one month ago
  • Lack of effective contraception during the study period for patients of childbearing potential
  • Patients under legal protective measures
  • Pregnant or breastfeeding women

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospices Civils de Lyon - Neurological Hospital - University Pain Clinic (CETD)

Bron, France, 69500

Actively Recruiting

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Research Team

L

Luis Garcia-Larrea, Doctor

CONTACT

N

Nathalie André-Obadia, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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