Actively Recruiting
Cortico-cortical Stimulation and Robot-assisted Therapy for Upper Limb Recovery After Stroke (CCS&RAT)
Led by I.R.C.C.S. Fondazione Santa Lucia · Updated on 2025-02-20
32
Participants Needed
1
Research Sites
162 weeks
Total Duration
On this page
Sponsors
I
I.R.C.C.S. Fondazione Santa Lucia
Lead Sponsor
U
Università degli studi di Roma Foro Italico
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to tested the effect of combination of a paired associative stimulation of two functional interconnected areas of the cerebral cortex (posterior-parietal cortex and primary motor cortex) with robot-assisted therapy in the recovery of upper limb after stroke.
CONDITIONS
Official Title
Cortico-cortical Stimulation and Robot-assisted Therapy for Upper Limb Recovery After Stroke (CCS&RAT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First ever chronic ischemic stroke
- Hemiparesis due to left or right subcortical or cortical lesion in the territory of the middle cerebral artery
- Severe or moderate residual upper limb impairment (Fugl-Meyer Assessment motor domain A/D score less than 52)
You will not qualify if you...
- History of seizures
- Severe general impairment or other serious diseases
- Current treatment with benzodiazepines, baclofen, or antidepressants
- Intracranial metal implants
- Cardiac pacemaker
- Pregnancy
- Orthopedic conditions preventing upper limb therapy
- Upper limb pain
- Cognitive impairment (Mini-Mental State Examination score less than 23)
- Presence of unilateral spatial neglect
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Santa Lucia Foundation
Rome, Italy, 00179
Actively Recruiting
Research Team
G
Giacomo Koch, prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here