Actively Recruiting
Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
Led by Université du Québec à Trois-Rivières · Updated on 2026-01-22
40
Participants Needed
2
Research Sites
164 weeks
Total Duration
On this page
Sponsors
U
Université du Québec à Trois-Rivières
Lead Sponsor
C
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Collaborating Sponsor
AI-Summary
What this Trial Is About
Thumb osteoarthritis or trapeziometacarpal osteoarthritis (TMO) is a common and painful form of hand arthritis that limits thumb mobility and hand function, affecting patients' quality of life. Although corticosteroids injections are a typical treatment, their effectiveness has been challenged, and side effects have been reported. Recent studies suggest that saline injections, usually considered inactive, might be a viable treatment option. The primary goal of this study is to compare the effectiveness of saline injections versus corticosteroids injections in reducing TMO-related pain and improving hand function. In this study, 40 people with TMO will be randomly assigned to receive either a corticosteroids or a saline injection, without them or the doctors performing the injection knowing which one was administered (double blind). If saline injections prove more effective, they could provide a less harmful and cheaper therapeutic alternative for TMO patients.
CONDITIONS
Official Title
Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Diagnosis of trapeziometacarpal osteoarthritis confirmed by X-ray
- Experiencing pain at the base of the thumb
- Attending physician recommends intra-articular corticosteroid injection
- Able to read, understand, and answer in French or English
You will not qualify if you...
- Received corticosteroid injections or surgery on the affected thumb within the last 12 months
- Thumb pain caused by trauma, rheumatoid arthritis, or De Quervain's tendonitis
- Currently pregnant or breastfeeding
- Known allergies to corticosteroid injection components or iodinated contrast media
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Centre Hospitalier de l'Université de Montréal - Physiatry
Montreal, Quebec, Canada, H2W 1T6
Actively Recruiting
2
Centre Hospitalier de l'Université de Montréal - Chirurgie plastique
Montreal, Quebec, Canada, H2X 0C1
Actively Recruiting
Research Team
T
Tokiko Hamasaki, PhD
CONTACT
C
Carlos Gevers-Montoro, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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