Actively Recruiting

Age: 18Years +
All Genders
NCT04737239

Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Led by Henry Ford Health System · Updated on 2026-03-02

300

Participants Needed

1

Research Sites

312 weeks

Total Duration

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AI-Summary

What this Trial Is About

Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment syndrome worldwide. There are currently no studies examining the effectiveness of corticosteroid injections in patients with normal (negative) EMG studies. The purpose of this study is to gain a better understanding of the duration of symptom improvement post corticosteroid injection in patients with negative or mild EMG studies. The Boston Carpal Tunnel Questionnaire will be given to patients undergoing corticosteroid injections for the treatment of carpal tunnel syndrome to assess their response to the injection. Investigators will collect data retrospectively. The Boston Carpal Tunnel Questionnaire (BCTQ) is administered as per standard protocol to all patients with CTS who have a negative or mild EMG study. The BCTQ assesses the patient's self-reported symptom severity and functional status. Investigators will analyze this data with respect to demographics as well as numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, Quick-Dash score, and grip strength score. The primary outcome will be the Boston Carpal Tunnel Questionnaire outcome score under the different EMG conditions.The secondary outcomes will be numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, QuickDash score, and grip strength score. Both outcomes will be examined in patients with negative or mild EMG readings. This information will allow orthopedic physicians to gain a better understanding of the duration of symptom improvement post-corticosteroid injection, allowing them to fine tune their treatment plans for CTS patients.

CONDITIONS

Official Title

Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who speak English
  • Patients who are 18 years or older
  • Patients who are clinically diagnosed with CTS
  • Patients who have a negative or mild EMG study
  • Patients who receive a corticosteroid injection after obtaining a negative or mild EMG study
Not Eligible

You will not qualify if you...

  • Patients who do not speak English
  • Patients who are younger than 18 years of age
  • Patients who have experienced previous trauma to the wrist
  • Patients who have had previous treatment for CTS including but not limited to corticosteroid injection or surgery
  • Patients with a moderate or severe EMG study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Henry Ford Health System

Detroit, Michigan, United States, 48202

Actively Recruiting

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Research Team

E

Elizabeth A Washnock-Schmid, B.S.

CONTACT

A

Aaron R Prater, M.S.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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