What is this study trying to find out about Carpal Tunnel Syndrome?

This study is examining how long symptom improvement lasts after corticosteroid injections in patients with negative or mild EMG studies for Carpal Tunnel Syndrome. Researchers aim to better understand treatment outcomes and help doctors improve care plans. The study is led by Henry Ford Health System.

Who may be eligible for this Carpal Tunnel Syndrome clinical trial?

Adults 18 years or older diagnosed with Carpal Tunnel Syndrome who speak English may be eligible. Participants must have negative or mild EMG results and receive corticosteroid injections. Those with prior wrist trauma or previous CTS treatments are not eligible. Please review eligibility criteria for more details.

Is there any cost to participate in this Carpal Tunnel Syndrome clinical trial?

Study-related care, including corticosteroid injections and all trial visits, is provided at no cost. However, personal travel and related expenses may vary and are not guaranteed to be covered.

Actively Recruiting

Age: 18Years +

All Genders

ID04737239

Corticosteroid Injection Effectiveness in Carpal Tunnel Patients With Negative or Mild EMG

Led by Henry Ford Health System · Updated on 2026-03-02

300

Participants Needed

Research Sites

39 weeks

Total Duration

AI-Summary

What this Trial Is About

Carpal Tunnel Syndrome CTS is the most common nerve entrapment condition worldwide. This study aims to better understand how long patients experience symptom improvement after corticosteroid injections, specifically in those with normal negative or mild EMG study results. Researchers will analyze patient responses based on the Boston Carpal Tunnel Questionnaire to assess symptom severity and functional status in these groups. Participants diagnosed with CTS who have negative or mild EMG studies and receive corticosteroid injections will be included. Data will be collected retrospectively from patients who completed the Boston Carpal Tunnel Questionnaire following their injections. The study compares outcomes such as numbness, nocturnal symptoms, muscle weakness or atrophy, and physical test results between these two EMG groups. During the study, patients self-reported symptoms and functional abilities will be assessed with the Boston Carpal Tunnel Questionnaire. Additional measurements include numbness in the median nerve area, muscle strength, Tinels and Phalens tests, two-point discrimination, QuickDash scores, and grip strength. This information will help physicians better tailor treatment plans for CTS patients based on EMG findings. The primary outcome is the questionnaire score over one year, with secondary outcomes covering various symptom and function measures.

CONDITIONS

Brief Title

Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Who Can Participate

Age: 18Years +

All Genders

Eligibility Criteria

You may qualify if you...

Patients who speak English
Patients who are 18 years or older
Patients who are clinically diagnosed with CTS
Patients who have a negative or mild EMG study
Patients who receive a corticosteroid injection after obtaining a negative or mild EMG study

You will not qualify if you...

Patients who do not speak English
Patients who are younger than 18 years of age
Patients who have experienced previous trauma to the wrist
Patients who have had previous treatment for CTS including but not limited to corticosteroid injection or surgery
Patients with a moderate or severe EMG study

Research Team

Elizabeth A Washnock-Schmid, B.S.

Aaron R Prater, M.S.

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