Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT04715984

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

Led by Vanderbilt University Medical Center · Updated on 2026-02-17

75

Participants Needed

1

Research Sites

426 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.

CONDITIONS

Official Title

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
  • Planned clinical electrode trajectory that contacts caudate
  • Age greater than or equal to 40
  • Diagnosis of Parkinson's disease
  • Able to participate in intraoperative testing
  • English speaking
Not Eligible

You will not qualify if you...

  • Age less than 40
  • Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
  • Movement disorder other than Parkinson's disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37212

Actively Recruiting

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Research Team

I

Isabel Long, BS

CONTACT

S

Sarah Bick, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment | DecenTrialz