Actively Recruiting
COsegregation of VARiants in Panel of Genes
Led by Institut Curie · Updated on 2025-04-06
3500
Participants Needed
57
Research Sites
1122 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the COVAR project is to classify reliably a maximum of VUS of the French database in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.
CONDITIONS
Official Title
COsegregation of VARiants in Panel of Genes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Index cases carrying a class 3 or 4 gene variant from the national French genetic database
- Age 18 years or older
- Signed written informed consent as an index case
- Relatives of an index case with or without cancer selected based on family structure
- Relatives aged 18 years or older
- Signed written informed consent as selected relatives
You will not qualify if you...
- Minors (under 18 years old)
- Persons deprived of liberty or under guardianship
- Lack of signed written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 57 locations
1
Institut Curie - Hopital Rene Huguenin
Saint-Cloud, Haut de Seine, France, 92210
Actively Recruiting
2
CHU Amiens - Hôpital Nord
Amiens, France, 80054
Actively Recruiting
3
ICO - Centre Paul Papin
Angers, France, 49933
Actively Recruiting
4
Centre Hospitalier d'Angoulème
Angoulême, France, 16959
Actively Recruiting
5
Institut Sainte-Catherine
Avignon, France, 84918
Actively Recruiting
6
CHU Besançon
Besançon, France, 25030
Actively Recruiting
7
Groupe Hospitalier Pellegrin
Bordeaux, France, 33076
Actively Recruiting
8
Institut Bergonié
Bordeaux, France, 33076
Actively Recruiting
9
Centre Hospitalier Jacques Coeur
Bourges, France, 18020
Actively Recruiting
10
CHU Morvan de Brest
Brest, France, 29200
Actively Recruiting
11
Centre François Baclesse
Caen, France, 14076
Actively Recruiting
12
Centre Hospitalier Hôtel Dieu
Chambéry, France, 73011
Actively Recruiting
13
Centre Jean Perrin
Clermont-Ferrand, France, 63011
Actively Recruiting
14
Hôpital Civil de Colmar
Colmar, France, 68024
Not Yet Recruiting
15
CHU de Dijon
Dijon, France, 21079
Actively Recruiting
16
CHU de Grenoble
Grenoble, France, 38043
Actively Recruiting
17
Groupe Hospitalier La Rochelle-Ré-Aunis
La Rochelle, France, 17019
Actively Recruiting
18
Hôpital Flaubert
Le Havre, France, 76083
Actively Recruiting
19
Centre Oscar Lambret
Lille, France, 59000
Actively Recruiting
20
Chru Lille
Lille, France, 59037
Actively Recruiting
21
CHU Dupuytren
Limoges, France, 87042
Actively Recruiting
22
Hospices Civils de Lyon
Lyon, France, 69229
Actively Recruiting
23
Centre Léon Bérard
Lyon, France, 69373
Actively Recruiting
24
Institut Paoli Calmettes
Marseille, France, 13009
Actively Recruiting
25
CHU La Timone
Marseille, France, 13385
Actively Recruiting
26
CHU Arnaud de Villeneuve
Montpellier, France, 34295
Actively Recruiting
27
Centre Catherine de Sienne
Nantes, France, 44202
Actively Recruiting
28
Centre Antoine Lacassagne
Nice, France, 06189
Actively Recruiting
29
Centre Hospitalier Georges Renon
Niort, France, 79021
Actively Recruiting
30
CHRU Caremeau
Nîmes, France, 30029
Actively Recruiting
31
Hôpital de la Source
Orléans, France, 45067
Actively Recruiting
32
Hôpital Saint-Antoine
Paris, France, 75012
Actively Recruiting
33
Groupe Hospitalier Pitié-Salpêtrière
Paris, France, 75013
Actively Recruiting
34
Hôpital Tenon
Paris, France, 75020
Actively Recruiting
35
Hôpital Saint-Louis
Paris, France, 75475
Actively Recruiting
36
HEGP
Paris, France, 75908
Actively Recruiting
37
CHU La Milétrie
Poitiers, France, 86021
Actively Recruiting
38
CHU de Reims
Reims, France, 51092
Actively Recruiting
39
ICC Courlancy
Reims, France, 51100
Actively Recruiting
40
Institut Jean Godinot
Reims, France, 51100
Actively Recruiting
41
Centre Eugène Marquis
Rennes, France, 35042
Actively Recruiting
42
CHU de Rouen
Rouen, France, 76031
Actively Recruiting
43
CHU Saint Etienne
Saint-Etienne, France, 42055
Actively Recruiting
44
ICO - Centre René Gauducheau
Saint-Herblain, France, 44804
Actively Recruiting
45
Institut de Cancérologie Strasbourg Europe ICANS
Strasbourg, France, 67033
Actively Recruiting
46
Hopital de Hautepierre - Hôpital Universitaire
Strasbourg, France, 67200
Actively Recruiting
47
Institut Claudius Regaud - IUCT - Oncopole
Toulouse, France, 31059
Actively Recruiting
48
CHU Bretonneau
Tours, France, 37044
Actively Recruiting
49
CH Simone VEIL
Troyes, France, 10003
Actively Recruiting
50
Centre Hospitalier de Valence
Valence, France, 26953
Actively Recruiting
51
Centre Alexis Vautrin
Vandœuvre-lès-Nancy, France, 54511
Withdrawn
52
CHU Nancy - Hôpital Brabois
Vandœuvre-lès-Nancy, France, 54511
Actively Recruiting
53
Gustave Roussy
Villejuif, France, 94805
Actively Recruiting
54
Institut Curie
Paris, Île-de-France Region, France, 75005
Actively Recruiting
55
CHU de Pointe à Pitre
Pointe-à-Pitre, Guadeloupe, 97110
Actively Recruiting
56
CHU de Fort de France
Fort-de-France, Martinique, 97261
Actively Recruiting
57
CHU Sud Réunion Saint-Pierre
Saint-Pierre, Reunion, 97410
Actively Recruiting
Research Team
S
Sandrine CAPUTO, PhD
CONTACT
I
Isabelle TURBIEZ, Project Manager
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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