Actively Recruiting
Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate
Led by The University of Texas Health Science Center, Houston · Updated on 2026-02-19
40
Participants Needed
1
Research Sites
341 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this trial is to evaluate if the use of Bone Morphogenic Protein(BMP)/Demineralized Bone Matrix (DBM) versus the use of autologous Iliac Crest Bone Graft (ICBG) will result in an increase in total cost effectiveness for patients undergoing alveolar bone graft (ABG) for Cleft Lip and Palate (CLP) and to see if patients who are treated with DBM/BMP will have reduced post-operative pain scores,reduced operative times,and similar rates of bone healing compared to conventional ICBG.
CONDITIONS
Official Title
Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with cleft lip and palate (unilateral or bilateral)
- Radiographically confirmed open bone defect of the alveolus
- Dentition evaluated and cleared by an orthodontist for alveolar bone graft surgery
You will not qualify if you...
- Patients without cleft lip and palate
- Previous failed repair of alveolar cleft
- Patients who have previously undergone successful alveolar bone graft
- Patients without an alveolar defect
- Parents who refuse to consent to randomization
- Patients with syndromic cleft lip and palate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
M
Matthew Greives, MD
CONTACT
T
Tien Do, DO
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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