Study of a Smartphone App and Smartwatch to Reduce Chronic Cough in Adults Aged 21 and Older

What this Trial Is About

Researchers are evaluating a smartphone-based Cough Management CM program designed to reduce cough frequency and burden in adults aged 21 to 80 years who have refractory or unexplained chronic cough. The study aims to determine if four weeks of using the CM feature in the CoughPro app can lower the objective cough rate compared to each participants one-week baseline. It also investigates whether the program decreases cough intensity and improves quality of life based on patient-reported scores using the Leicester Cough Questionnaire and PGI-S. Participants will use the CoughPro wellness app, which includes behavioral lessons based on cough suppression therapy to help recognize and control the urge to cough. They will wear a Hyfe CoughMonitor smartwatch continuously for six weeks one week for baseline cough monitoring, four weeks of the intervention using the CM program, and one week of follow-up. The smartwatch passively monitors cough frequency without recording audio. The program is delivered entirely through participants devices. During the study, participants will complete online questionnaires at baseline and after four weeks of intervention. They will also take part in a brief exit interview before returning the smartwatch and receiving compensation. Researchers will measure changes in cough rate, cough intensity, and patient-reported cough burden. The total participation time is six weeks, including baseline, intervention, and follow-up periods.

Cough Management Wellness App for Refractory or Unexplained Chronic Cough