Actively Recruiting
Countermeasures to Circadian Misalignment
Led by Colorado State University · Updated on 2025-07-24
32
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
Sponsors
C
Colorado State University
Lead Sponsor
U
University of Colorado, Denver
Collaborating Sponsor
AI-Summary
What this Trial Is About
Insufficient sleep and circadian misalignment are independent risk factors for the development of obesity and diabetes, yet few strategies exist to counter metabolic impairments when these behaviors are unavoidable. This project will examine whether avoiding food intake during the biological night can mitigate the impact of circadian misalignment on metabolic homeostasis in adults during simulated night shift work. Findings from this study could identify a translatable strategy to minimize metabolic diseases in populations that include anyone working nonstandard hours such as police, paramedics, firefighters, military personnel, pilots, doctors and nurses, truck drivers, and individuals with sleep disorders.
CONDITIONS
Official Title
Countermeasures to Circadian Misalignment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 35 years, including men and women with equal representation
- Body Mass Index (BMI) between 20.0 and 24.9 (normal weight range)
- Physical activity level from inactive to habitual moderate activity
- Habitual sleep duration between 7 and 9.25 hours
- Lived at Denver altitude or higher for at least 3 months before the study
You will not qualify if you...
- Presence of any significant medical, psychiatric, or sleep disorder
- Use of prescribed medications, supplements, or illicit drugs within one month before the study
- History of shift work in the year before the study or travel across more than one time zone in the three weeks before the study
- Women with prior gynecological problems, less than one year post-partum, breastfeeding, or pregnant
- Non-English speakers due to lack of translator availability
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Colorado State University
Fort Collins, Colorado, United States, 80523
Actively Recruiting
Research Team
J
Josiane L Broussard, PhD
CONTACT
E
Ellen Lyon, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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