Actively Recruiting
COVID-2019 Vaccine Immune Response Base on Single Cell Multi-Omics
Led by RenJi Hospital · Updated on 2021-06-03
50
Participants Needed
1
Research Sites
304 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In recent years, single-cell high-throughput sequencing technology has developed rapidly and is widely used in research related to the immune system, breaking traditional cognition and gaining a new understanding of immune cell classification. In particular, the emerging single cell RNA sequencing (scRNA-seq) provides new ideas for the study of cell heterogeneity in multicellular organisms. Analyzing the changes in the expression profile of the cell transcriptome at the single-cell level can clearly show the changes in the trajectory of individual cells, reveal new cell types, and discover the potential functions of immune cells. Therefore, this study intends to recruit healthy adults and use multi-omics techniques such as single-cell sequencing to systematically classify the peripheral blood mononuclear cells of healthy adults to provide a basis for further disease-related research.
CONDITIONS
Official Title
COVID-2019 Vaccine Immune Response Base on Single Cell Multi-Omics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18 to 50 years
- No history of major diseases
- No bacterial or viral infection in the past 3 months
- No recent surgery or trauma
- No history of smoking or alcoholism
- No immune system disease
You will not qualify if you...
- Infectious diseases
- Tumor diseases
- Hematological diseases
- History of hypertension and diabetes
- Autoimmune diseases
- History of liver and kidney insufficiency
- History of cardiovascular diseases
- Pregnancy or breast-feeding
- Past and current use of immunosuppressive drugs
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cardiology, Ren Ji Hospital
Shanghai, China
Actively Recruiting
Research Team
J
Jun Pu, MD,PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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